18th International Symposium on Translational Research in Oncology (TRANSONC)
DRAFT PROGRAMME
Wednesday, 24th September 2025 Lansdowne Suite, Herbert Park Hotel
Registration from 08:30 RCPI 4 external CPD credits
Wednesday, 24thSeptember 2025, Lansdowne Suite, Herbert Park Hotel
Registration from 08:30 TBC: RCPI external CPD credits
09:00 – 09:15 Welcome and Introduction – Prof John Crown, St. Vincent’s Hospital, Dublin
SESSIOn 1: Session Chair – Prof. Sara Hurvitz, Fred Hutch Cancer Center
09:15 – 09:45 Topic: ctDNA technology (ongoing studies, controversies in its use in routine practice for cancer
Dr. Heather Parsons, Dana-Farber Cancer Institute
09:45 – 10:15 Topic: Epigenetic modifiers
Dr. Karen Chichowski, Harvard Medical School
10:15 – 10:45 Topic: Disseminated Tumour Cells and the tumour microenvironment
Dr. Cyrus Gajar, Fred Hutch Cancer Center
10:45 – 11:00 Coffee break
SESSIOn 2: Session Chair – Prof. Sara Hurvitz, Fred Hutch Cancer Center
11:00 – 11:30 Topic: Vepdegestrant
Dr. Janaki Parameswaran, Senior Medical Director, Arvinas
11:30 – 12:00 Topic: Atirmociclib
Pfizer
12:00 – 12:30 Topic: TBC
Speaker TBC
12:30 – 13:30 Lunch
SESSIOn 3: Session Chair – Prof. John Crown, St Vincent’s Hospital; DCU; UCD
13:30 – 14:00 Topic: Novel targeted therapies
Dr. Neil O’Brien, David Geffen School of Medicine, UCLA
14:00 – 14:30 Topic: Novel targeted therapies
Dr. Martina McDermott, David Geffen School of Medicine, UCLA
KEYNOTE PRESENTATION
14:30 – 15:15 Topic TBC
Dr. Dennis J. Slamon, 2019 Lasker Award Winner, Director of Clinical/Translational Research, Director of the Revlon/UCLA Women’s Cancer Research Program at JCCC. Professor of Medicine, Chief, Division of Hematology/Oncology.
15:15 – 15:30 Coffee break
SESSIOn 4: Session Chair – Prof. John Crown, St Vincent’s Hospital; DCU; UCD
15:30 – 16:00 Topic: Hapatobiliary Cancer
Dr. Grainne O’Kane, Pat Smullen Chair in Pancreatic Cancer, University College Dublin
16:00 – 16:30 Topic: Lung cancer
Dr. Patrick Forde, Trinity St. James’ Cancer Institute, Dublin
16:30-17:00 Topic: IO toxicity
Dr. Jarushka Naidoo, Beaumont Hospital & Royal College of Surgeons in Ireland.
Thursday, 25th September 2025 Lansdowne Suite, Herbert Park Hotel
Registration from 08:30 TBC: RCPI external CPD credits
ARTIFICIAL INTELLIGENCE IN MEDICINE
Session Chair – Prof. Mark Pegram, Stanford University School of Medicine
09:00 – 09:30 Topic: Targeting mutant ESR1
Speaker TBC
09:30 – 10:00 Topic: Inavolisib in PI3K mutant ER+ breast cancer
Speaker TBC
10:00 – 10:30 Topic: CID-078 – cyclin A/B, RxL inhibitor
Circle Pharma
10:30 – 10: 45 Coffee break
SESSION 2: Session Chair – Prof. Mark Pegram, Stanford University School of Medicine
10:45 – 11:15 Topic: Artificial Intelligence (AI) in Pathology
Dr Donal O’Shea, CEO, Deciphex
11.15 – 11:45 Topic: Radiomics Artificial Intelligence
Dr Hiruka Itakura, Stanford University School of Medicine
11.45 – 12:15 Topic: AI in Pathology
Prof. Hamid Tizhoosh, Department of Artificial Intelligence and Informatics, Mayo Clinic
12:15 – 13:15 Lunch
WHAT CAN WE LEARN FROM SPATIAL PROFILING OF TUMOUR TISSUES
Session Chair – Prof. Lajos Pusztai, Yale School of Medicine
13:15 – 13:45 Topic: GeoMx spatial transcriptomic technology
Nanostring
13:45 – 14:15 Mixed molecular subtypes in ER-heterogeneously positive breast cancer
Prof. Lajos Pusztai, Yale School of Medicine
14:15 – 14:45 Spatial predictors of response to neoadjuvant IO therapy-
Dr. Raza Ali, Cancer Research UK, Cambridge Institute
14:45-15:15 Single cell sequencing landscape of breast cancer
Dr. Isaac Chan, Simmons Comprehensive Cancer Centre, University of Texas Southwestern
15:15 – 15:30 Coffee break
ARTIFICIAL INTELLIGENCE AIDED DRUG DEVELOPMENT
Session Chair – Prof. Lajos Pusztai, Yale School of Medicine
15:30 – 16:00 Deep Learning for Drug Discovery: Accelerating Innovation from Data to Molecules
Dr. Mostafa Ahmed, Associate Director, CADD, Atomwise
16:00 – 16:30 Topic: AI tools to accelerate drug development
Dr.Melissa Davis, Head of Computational Biology,Isomorphic labs
16:30– 17:00 Topic: AI-image guided immunotherapy.
Dr. Jeffrey Venstrom, Ambient Bio
Friday 26th September 2025 Lansdowne Suite, Herbert Park Hotel
Registration from 8:30 TBC: RCPI external CPD credits
SESSION 1: Session Chair – Prof Robert Kerbel, University of Toronto
09:00 – 09:30 Topic TBC
Prof. Yuval Shaked, Director of the Rappaport-Technion Integrated Cancer Center
09:30 – 10:00 Topic: c-kit ADC / mouse models
Prof. Kabir Khan, UK
10:00 – 10:30 Topic: Prostate/GI NETS cancers
Dr. Iacovos Michael, Sunnybrook Research Institute, University of Toronto.
10:30 – 10:45 Coffee break
SESSION 2: Session Chair – Prof Robert Kerbel, University of Toronto
10:45– 11:15 Topic: VEGF and PD-1 Bi-specific
Dr. Claudia-Nanette Gann, Global Medical Lead, BionTech
11:15 – 11:45 Topic: Targeting the TME in HCC
Dr. Rich Finn, Geffen School of Medicine, UCLA
KEYNOTE PRESENTATION
11:45 – 12:30 Topic: TBC
Dr. Douglas Hanahan, 2025 Winner of the Pezcoller Foundation–American Association for Cancer Research (AACR) International Award for Extraordinary Achievement in Cancer Research, Member of the Royal Society of London and Ludwig Distinguished Scholar, Ludwig Institute for Cancer Research
12:30 – 13:30 Lunch
SESSION 3
Session Chair – Dr. Dimitrios Tryfonopoulos, Medical Oncologist, Saint Savvas Anticancer Hospital, Athens
13:30 – 14:00 Topic: TBC
Immunocore
14:00 – 14:30 Topic: TBC
Dr. Thomas Bogenrieder, CMO, Abalos Therapeutics
14:30 – 15:00 Topic: TBC
Dr. Giuseppe Gullo, Executive Medical Director, Clinical Development, Replimune
15:00– 15:15 Coffee break
SESSION 4
Session Chair – Prof William Gallagher, AICRI & University College Dublin
15:15 – 15:45 Banf-1 inhibitor
Dr. Ken O’Byrne, Queensland University of Technology; Princess Alexandra Hospital
15:45 – 16:15 Topic: TBC
Prof. Denis Collins, Dublin City University
Speaker TBC
Meeting ends