Professor John Crown was awarded the DCU President’s Impact Award for research he leads at the National Institute for Cellular Biotechnology (NICB) to improve the treatment options available to women with metastatic HER2-positive breast cancer. Under his leadership, a new drug combination to treat women with this type of breast cancer, that is based on prior preclinical studies from the Cancer Clinical Research Trust (CCRT) research team based in the NICB, has entered clinical development in a recently opened Phase 1 clinical trial named CAROLINE-1. The CAROLINE-1 study received support from CCRT, The Caroline Foundation, BreastPredict and Puma Biotechnology Inc.

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